obg.cuhk.edu.hk 30 August 2015
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Staff Details for Professor CHIM,Stephen Siu-chung

Contact details for Professor Chim are shown below

Current Position:Associate Professor
Office Phone:2632 1324
Fax:2636 0008

Qualifications: Ph.D

Journal Articles

Potential application of fetal epigenetic markers on the non-invasive prenatal detection of chromosomal abnormality.
Chim SSC
Clin Chem Lab Med 2014;52(5): 585 - 588
Proteomic Analysis Reveals Platelet Factor 4 and Beta-thromboglobulin as Prognostic Markers in Severe Acute Respiratory Syndrome.
Poon TCW, Pang RTK, Chan AKC, Lee NLS, Chiu RWK, Tong YK, Chim SSC, Ngai SSM, Sung JJY, Lo DYM
Electrophoresis 2012;33(12): 1894 - 1900
Systematic Identification of Spontaneous Preterm Birth-Associated RNA Transcripts in Maternal Plasma.
Chim SSC, Lee WS, Ting YH, Chan OK, Lee SWY, Leung TY
PLos ONE 2012;7(4): e34328
CHD5 Downregulation Associated with Poor Prognosis in Epithelial Ovarian Cancer.
Wong RRY, Chan LKY, Tsang PT, Lee CWS, Cheung TH, Yim SF, Siu NSS, Lee SNC, Yu MMY, Chim SSC, Wong YF, Chung TKH
Gynecol Obstet Inves 2011;72(3): 203 - 207
Epigenetic Regulation of Neonatal Cardiomyocytes Differentiation.
Kou CYC, Lau SLY, Au KW, Leung PY, Chim SSC, Fung KP, Waye MMY, Tsui SKW
Biochem Bioph Res Co 2010;400(2): 278 - 283
Systematic Identification of Placental Epigenetic Signatures for the Noninvasive Prenatal Detection of Edwards Syndrome.
Tsui DWY, Lam DYM, Lee CWS, Leung TY, Lau TK, Lau ET, Tang MHY, Akolekar R, Nicolaides KH, Chiu RWK, Lo DYM, Chim SSC
PLos ONE 2010;5(11): e15069
Presence of donor-derived DNA and cells in the urine of sex-mismatched hematopoietic stem cell transplant recipients: implication for the transrenal hypothesis.
Hung ECW, Shing TKF, Chim SSC, Yeung PC, Chan RWY, Chik KW, Lee V, Tsui NBY, Li CK, Wong CSC, Chiu Rossa WK, Lo DYM
Clin Chem 2009;55(4): 715 - 722
Role of monoamine oxidases in the exaggerated 5-hydroxytryptamine-induced tension development of human isolated preeclamptic umbilical artery.
Seto SW, Lam HY, Lau WS, Au ALS, Lam TY, Chim SSC, Ngai SSM, Chan SW, Leung TY, Yeung JHK, Kong SK, Leung GPH, Lee SMY, Kwan YW
Eur J Pharmacol 2009;605(1-3): 129 - 137
Detection and Characterization of Placental MicroRNAs in Maternal Plasma.
Chim SSC, Shing TKF, Hung ECW, Leung TY, Lau TK, Chiu Rossa WK, Lo DYM
Clin Chem 2008;54(3): 482 - 490
Systematic Search for Placental DNA-Methylation Markers on Chromosome 21: Toward a Maternal Plasma-Based Epigenetic Test for Fetal Trisomy 21.
Chim SSC, Jin SN, Lee TYH, Lun FMF, Lee CWS, Chan LYS, Jin Yongjie, Yang NN, Tong YK, Leung TY, Lau TK, Ding CM, Chiu Rossa WK, Lo DYM
Clin Chem 2008;54(3): 500 - 511
Hypermethylation of RASSF1A in Human and Rhesus Placentas.
Chiu Rossa WK, Chim SSC, Wong IHN, Wong CSC, Lee CWS, To KF, Tong JHM, Yuen KC, Shum ASW, Chan JKC, Chan LYS, Yuen WF, Tong YK, Weier JF, Ferlatte C, Leung TN, Lau TK, Lo KW, Lo DYM
Am J Pathol 2007;170(3): 941 - 950
Modulation by simvastatin of iberiotoxin-sensitive, Ca2+-activated K+ channels of porcine coronary artery smooth muscle cells.
Seto SW, Au ALS, Lam TY, Chim SSC, Lee SMY, Wan S, Tjiu DCS, Shigemura N, Yim APC, Chan SW, Tsui SKW, Leung GPH, Kwan YW
Brit J Pharmacol 2007;151(7): 987 - 997
Quantitative aberrations of hypermethylated RASSF1A gene sequences in maternal plasma in pre-eclampsia.
Tsui DWY, Chan AKC, Chim SSC, Chan LW, Leung TY, Lau TK, Lo DYM, Chiu Rossa WK
Prenatal Diag 2007;27(13): 1212 - 1218
Reply to "STOX1 is not imprinted and is not likely to be involved in preeclampsia".
Van Dijk M, Van Bezu J, Chim SSC, Lo DYM, Blankenstein MA, Oudejans CBM
Nat Genet 2007;39(3): 280 - 281
Calcyclin binding protein promotes DNA synthesis and differentiation in rat neonatal cardiomyocytes.
Au KW, Kou CYC, Woo AYH, Chim SSC, Fung KP, Cheng CHK, Waye MMY, Tsui SKW
J Cell Biochem 2006;98(3): 555 - 566
Hypermethylated RASSF1A in Maternal Plasma: A Universal Fetal DNA Marker that Improves the Reliability of Noninvasive Prenatal Diagnosis.
Chan AKC, Ding CM, Gerovassili A, Yeung SW, Chiu Rossa WK, Leung TN, Lau TK, Chim SSC, Chung GTY, Nicolaides KH, Lo DYM
Clin Chem 2006;52(12): 2211 - 2218
Noninvasive prenatal detection of fetal trisomy 18 by epigenetic allelic ratio analysis in maternal plasma: Theoretical and empirical considerations.
Tong YK, Ding CM, Chiu Rossa WK, Gerovassili A, Chim SSC, Leung TY, Leung TN, Lau TK, Nicolaides KH, Lo DYM
Clin Chem 2006;52(12): 2194 - 2202
Serum amyloid A is not useful in the diagnosis of severe acute respiratory syndrome.
Pang RTK, Poon TCW, Chan AKC, Lee NLS, Chiu Rossa WK, Tong YK, Chim SSC, Sung JJY, Lo DYM
Clin Chem 2006;52(6): 1202 - 1204
Serum Proteomic Fingerprints of Adult Patients with Severe Acute Respiratory Syndrome.
Pang RTK, Poon TCW, Chan AKC, Lee NLS, Chiu Rossa WK, Tong YK, Wong RMY, Chim SSC, Ngai SSM, Sung JJY, Lo DYM
Clin Chem 2006;52(3): 421 - 429
A simple and rapid approach for screening of SARS-coronavirus genotypes: an evaluation study.
Chung GTY, Chiu Rossa WK, Cheung JLK, Jin Yongjie, Chim SSC, Chan PKS, Lo DYM
BMC Infect Dis 2005;5: 87
Detection of the placental epigenetic signature of the maspin gene in maternal plasma.
Chim SSC, Tong YK, Chiu Rossa WK, Lau TK, Leung TN, Chan LYS, Oudejans CBM, Ding CM, Lo DYM
Proc Natl Acad Sci USA 2005;102(41): 14753 - 14758
ACE2 Gene Polymorphisms Do Not Affect Outcome of Severe Acute Respiratory Syndrome.
Chiu Rossa WK, Tang NLS, Hui DSC, Chung GTY, Chim SSC, Chan AKC, Sung MYM, Chan Louis YS, Tong YK, Lee CWS, Chan PKS, Lo DYM
Clin Chem 2004;50(9): 1683 - 1686
Systematic micro-array based identification of placental mRNA in maternal plasma: towards non-invasive prenatal gene expression profiling.
Tsui NBY, Chim SSC, Chiu Rossa WK, Lau TK, Ng EKO, Leung TN, Tong YK, Chan AKC, Lo DYM
J Med Genet 2004;41(6): 461 - 467

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